Merging CRISPR Editing and single cell sequencing technologies

Keynote address by the Novartis Institutes for Biomedical Reseach

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SMi's conference on 3D Cell Culture will take place on 21st and 22nd February 2018 in London UK and feature a keynote address from Max Salick, Postdoctoral Researcher, Novartis Institutes for Biomedical Research.

MERGING CRISPR-EDITING AND SINGLE CELL SEQUENCING TECHNOLOGIES TO UNCOVER THE BIOLOGY OF HUMAN NEURODEVELOPMENTAL DISEASES IN 3D: CASE STUDIES WITH ZIKA VIRUS AND TUBEROUS SCLEROSIS

Max Salick

Max Salick, Postdoctoral Researcher, Novartis Institutes For Biomedical Research

  • CRISPR-engineered human stem cell lines mimic disease phenotypes during 3D cerebral organoid differentiation
  • Selective removal of target genes in cerebral organoids reveals the biology of Zika virus infection
  • Whole-genome CRISPR screens enable the discovery of new proteins linked to tropism of emerging infectious diseases
  • Single cell sequencing allows researchers to investigate cell-type specific effects of mutations, treatments, or other perturbations in complex 3D tissues

    Further details available at http://www.3d-CellCulture.com/3Dnet 
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    Teri Arri

    Senior Marketing Manager at SMi Group, SMi Group

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